Yes you can do stuff like disable indexing, disable system restore that speed things up. HERE is a guide to optimizing ssds that is pretty good.
If you have a lot of ram, you will rarely if ever use the paging file so you can even move it to your hdd. Some don't even keep one, but I do just in case -- don't want a bsod.
You can install programs to your Fusion IO and once the program is installed check that the temp files are also directed there either during install or later through program preferences depending on the program.
Message edited by Realbeast on 02-02-2012 at 10:59:42 PM
Yes, ALWAYS advised to do a fresh install. One of the most common problems in Win7 migration to SSD seems to be the migration causing unexpected results, which is solved through a fresh install in any event.