Headphone static while in-game

I've been getting static through my headphones whenever I run a game on my PC. I mainly notice it when I'm playing StarCraft 2 or Skyrim, but I don't really hear it when playing League of Legends. I can listen to music and other things without any problems at all. It's especially bad when plugged into the front panel. I've read in other threads that it could be a bad ground in the case, although I find it weird that I only hear it in-game. Any ideas to fix this?

Specs:
Case (CoolerMaster HAF 922 Gaming Case - Black))
Processor (Intel® Core™ i7-2600K Processor (4x 3.40GHz/8MB L3 Cache)
Motherboard (ASUS P8Z68-V LX -- Lucid Virtu Technology))
Memory (8 GB [4 GB X2] DDR3-1600 Memory Module - Corsair))
Video Card (NVIDIA GeForce GTX 560 - 2GB - Single Card))
Sound Card (3D Premium Surround Sound Onboard))
Primary Hard Drive (500 GB HARD DRIVE -- 16M Cache, 7200 RPM, 6.0Gb/s - Single Drive))
Headset (Thermaltake SHOCK Spin Gaming Headset)