Desktop won't power on or boot

I just returned from a long trip, and my computer will no longer boot. It was having some issues before I left, but someone recommended unplugging the PSU from the wall, holding the power button for 10 seconds and then plugging back in and turning it on which worked then, but does not work now.
When I plug the system in now and try to power on nothing happens. The fans don't spin, the power button LED never turns on, there are no beeps, or blinking lights, absolutely nothing happens. The only sign of life is that the Motherboard LED is on and red whenever the PSU is on. I thought it may have been the power supply so I sent that back in, and have the new one installed, but all the same problems still apply.
I also tried unplugging the power button from the case and trying to use a metal screwdriver to get the motherboard to power on, but that also didn't have any effect. I've already unplugged and plugged back in everything from the motherboard back to the PSU. Everything is plugged in tightly and correctly.
I tried using the reset button instead of the power button as well, but nothing happened.
Before this the computer had been running pretty smoothly for a little over a year, and only started having trouble turning on after being shut off just before I left.
Does this sound like a motherboard problem, or does anyone have any suggestions of what to try next?
At this point I'm debating whether or not to take it all apart and basically rebuild it, testing everything along the way, or just finding some local computer repair service and taking it to them. I'm not exactly great with computers, but I've been trying to learn so I'm a bit frustrated that after having everything working smoothly it just won't even power on now, and I can't figure out why. \

TLDR: Computer won't boot, PSU is brand new, everything's been plugged and unplugged, motherboard LED is red, no fans turning on or beeps, and the computer worked very well for some time before this.

PC specs:
Motherboard: MSI Z170A gaming m5
RAM: Corsair Vengeance LPX 8GB (2x4gb) ddr4 dram 3000mhz
CPU: intel core i5-6600k 3.50ghz (skylake) socket lga 1151 processor
GPU: Zotac - Nvidia Geforce Gtx 980 Amp! Edition 4gb Gddr5
PSU: evga supernova 1050 GS 80+gold
Reply to gamer4god
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More about desktop power boot
  1. Take the motherboard out of the case and set it on the motherboard box. See if it works as it could be the motherboard is grounding on the case. If it still has the same problem a new motherboard would by the best option. I suggest waiting till the 5th to see if the Z370 supports the older CPU. Least that way you have some great upgrade options.
    Reply to elbert
  2. elbert said:
    Take the motherboard out of the case and set it on the motherboard box. See if it works as it could be the motherboard is grounding on the case. If it still has the same problem a new motherboard would by the best option. I suggest waiting till the 5th to see if the Z370 supports the older CPU. Least that way you have some great upgrade options.


    Thanks for the suggestion! I will give that a try once I get back next weekend, and see if it works.
    Reply to gamer4god
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