Does not matter if components are installed or not, all OC is done in BIOS (some boards have utility programs that can help with that too).
OC is made to increase performance - but if you don't need it, it does not make sense - like would you use Ferrari to ride 10 mph? So get your machine running, and see what performance you get. If you get enough FPS, there's no point to OC. If you are not satisfied with what you get, you can then try OC.