It can't boot from that drive.
A regular SATA III drive will work no problem.
Thank you for the quick response!
Oh really? So I can't use it as a primary hard-drive at all?
And if so, is it because of the rather old motherboard or is this true in general for that hard-drive?
It's because of the age of that board.
Even one generation newer...a Z77, for instance, can't boot from that.
It's like if you buy a new Z270 board today...can it boot from whatever SuperZoom drive and interface we'll be using in 2025? Doubtful.