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Graphic cards compatible to my motherboard?

How do I know if my motherboard supports the graphic card I want to buy?
I have ASUS M5A78L/USB3 and I'd like to buy MSI Radeon R9 380.
My motherboard has a PCIe x16 2.0 and the graphic card is a PCIe x16 3.0, will that work? Is there something else I need to think about?
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  1. Best answer
    Yes it's 100% compatible , and no loss in performance using it in a 2.0 slot.
    https://www.pugetsystems.com/labs/articles/Impact-of-PCI-E-Speed-on-Gaming-Performance-518/
  2. SR-71 Blackbird said:
    Yes it's 100% compatible , and no loss in performance using it in a 2.0 slot.
    https://www.pugetsystems.com/labs/articles/Impact-of-PCI-E-Speed-on-Gaming-Performance-518/


    Thank you! :)
  3. Glad to help.
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