Not extra careful. Just reasonably careful. Lots of bend to them. You don't want to bend too much at the fittings/connections to the pump and the radiator. Cracks are bad generally speaking. Do you have a picture? Corsair has great service so you can RMA it if cracked. There is a protective mesh covering on the tubes just to prevent wear if something is touching the tube(s). Many automotive radiator hoses have the same thing.
They are fairly bendy (I have an H100i), the only thing you have to worry about would be the fittings. You would know how much bending is too much, its a fairly flexible unit. If the tubing were to crack that is grounds for an RMA.