voltoid27 said: I had a slightly OC'd 2GB DDR3 R7 250 at one point on a CX430M PSU and it had no trouble whatsoever. The 250 only pulls 75W anyway so you'll be fine
ChumP said: Despite the low quality of your VS 450 , the R7 250 is not a power hungry so it should work.Can you tell us your other PC specs?
ChumP said: You're good to go then , the power draw is well within the limits of your VS 450. Good luck.